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Tramadol for sale

Buy Tramadol- The potent and most effective painkiller medicine

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Generic Name : Tramadol Brand Name : M-Tram
Strength(s) : 50mg / 100mg Expiry : 2019
Delivery : 10 - 12 Days Price : $ 0.80 Per Pill

Tramadol is derived synthetically from codeine which is a phenanthrene alkaloid of opium. An important fact to note is that it is not a narcotic. It is expensive but works extremely well in relieving painful conditions. It was launched more than two decades back and it still continues to be a drug of choice to relieve pain.

It comes as capsules, tablets, suppositories and liquids for oral administration. OL-Tram and M-Tram are the most commonly used brand names for this pain medication.

Chemically, it is cyclohexanol. Recently in 2013, studies were even made to use in the distressing condition of premature ejaculation. It is a 4-phenyl piperidine analogue of codeine that is approved by Food and Drug Administration of USA for adult use in 1995.

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  • Action Mechanism of generic tramadol

    • This pain killer medicine works at the mu receptors reversibly which is the same site that accepts opioid medicines. These receptors are located in the higher centers of the brain as well as spinal cord. A part of its analgesic action is also because it inhibits noradrenaline and serotonin uptake. Noradrenaline and serotonin are classical neurotransmitters. The former is also a local hormone as it acts at the site of its synthesis. It is rapidly absorbed in the liver. Then, it is metabolized by CYP450 system to an active compound with analgesic action. The half life is around 6 hours. It is basically a centrally acting analgesic. It is more superior to opioids as it does not bind irreversibly to mu receptors. Moreover, it is not just a migraine specific medication. It also acts an alpha-2 agonist. A metabolite O-desmethyl binds to opioid receptors with a greater affinity than the parent compound and could significantly bring about analgesic effects. Animal and human studies have also shown that it has a selective spinal and local anesthetic action on peripheral nerves.
  • Benefits of using Tramadol pain killer

    • Alleviation of moderate to moderately severe pain is the most significant benefit besides being a painkiller, it is also used in restless legs syndrome that is a condition which might cause sciatic pain and intense symptoms at night, leading to sleeplessness. It is used to provide short term relief of acute pain. The patients suffering from Rheumatoid Arthritis and fibromyalgia and also Labor pain, motor neuron disease and pain due to terminal cancer can also be treated with the help of tramadol, It is a very safe medication if it is taken only two days per week. It can also be combined with acetaminophen for enhanced analgesic effects. Slight euphoria is also noticed with the usage and It has a low addiction potential. Owing to this, effective pain management can also be done in children. Another advantage of this medicine is that it does not have a ceiling effect which implies that there is no dose beyond which there is no additional analgesic effect.
  • Dosage of pain reliever Tramadol pills

    • • It is effective orally, rectally, intravenously or epidurally. Most commonly, oral route is followed.
      • Initially for oral drug administration, It should be given in the dosage of 75 mg along with 650 mg Acetaminophen every 4 to 6 hours.
      • Maximum dosage of 300 mg per day and 2600 mg Acetaminophen for up to 5 days. Food delays the plasma peak time, so it is advisable to take on empty stomach.
      • Adjust the dosage to 200 mg and 50 mg for renal and hepatic impairment respectively.
      • For children, the dosage is 1 to 2 mg/kg orally and intravenously.
  • Precautions while using tramadol pain reliever

    • It is one of the most commonly used painkillers to relieve pain after complicated surgeries. However, certain cautions need to be exercised while taking this medicine.
      • Use this pills with care in patients who are at risk for seizures or respiratory depression.
      • Increased intracranial pressure or head injury are the conditions in which should be avoided.
      • Patients of acute abdominal conditions, renal impairment and hepatic diseases are not ideal candidates for administering this medication.
      • Tricyclic antidepressants, selective serotonin reuptake inhibitors and opioids should not be used concurrently as it can lead to seizures.
      • Geriatric patients older than 75 years of age should not be given more than 300 mg per day in divided doses.
      • In patients with creatinine clearance less than 30 ml per minute, the dosing interval should be increased to 12 hours. Maximum daily dose for them is 200 mg.
      • Since it is mainly metabolized in liver, patients of cirrhosis should be given only 50 mg every 12 hours.
      • Previous history of drug abuse should be seriously considered while administering this medication because of its low abuse potential. It is not a controlled substance.
      • Patients who are allergic to codeine or other opioids should not be given anaphylactoid reactions.
      • Respiratory status should be monitored at regular intervals if patient has respiratory depression.
      • Alcohol should be strictly disallowed in patients with this tablets.
      • The dosage of this pills should be titrated slowly to minimize adverse effects.
  • Side Effects of Tramadol pain killer medication

    • Although there are a comparatively harmless medicine, it has certain adverse reactions mentioned below.

      • Dizziness
      • Sedation
      • Nausea
      • Vomiting
      • Constipation
      • Seizures and habituation when used with antidepressants
      • Insomnia or sleepiness
      • Increased sweating
      • Pruritus
      • Dry mouth
      • Hepatotoxicity
      • Anorexia
  • User Reviews for pain killer medication

    • I had fibroids in my uterus because of which I had to undergo a hysterectomy operation, that is, removal of uterus. Fibroids are very common in females and layman terminology it refers to small cysts in the ovary. I was very apprehensive for this operation. However, I did not even come to know of the surgery because of the unique analgesic of medicine. Had it not been for this tablets, I have no clue how complicated and painful the surgery would have been. The doctor gave the same medicine to my daughter even when she faced her labor pain. She had a painless delivery just because of this pain killer. Buy Tramadol it is easily available for sale at You can even buy tramadol online without any prescription and it would be shipped at your doorstep.


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